The incidence of cardiovascular disease increased profoundly in PLWHA, mainly because of improved life expectancy and quality by the institution of HAART. However, this still remain an underdiagnosed issue and challenge still at large at providing an adequate and comprehensive risk factors management. Pathophysiological, clinical and therapeutic factors interacts one another and cause increased cardiovascular disease risk in this population.
Chronic inflammation especially poses a challenging yet promisingly manageable risk for cardiovascular event, such presented by the JUPITER trial. Treatment of chronic inflammation by means of statins provides an opportunity to treat chronic inflammation and reduces cardiovascular risks. Dyslipidemia, another important causative factor for cardiovascular event must be managed accordingly in line with the recommendation from NCEP-ATP III and adjusted with specific recommendation from IDSA.
Pertinent to the hospitalized PLWHA, thrombosis was an important cause of cardiovascular event. Its management was critical in terms of reducing morbidity and mortality for the hospitalized PLWHA. Risk assessment and prophylactic management of thrombosis using anticoagulant are important efforts to be implemented comprehensively. Further researches are needed to confirm this recommendation.
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Pertinent to the hospitalized PLWHA, thrombosis was an important cause of cardiovascular event. Its management was critical in terms of reducing morbidity and mortality for the hospitalized PLWHA. Risk assessment and prophylactic management of thrombosis using anticoagulant are important efforts to be implemented comprehensively. Further researches are needed to confirm this recommendation.
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